DNAstackSearch Workflows
Whole Genome Sequencing Variant Pipeline
Analyze human PacBio whole genome sequencing (WGS) data to produce sequence alignment and variant calls for a sample or cohort.
alignment
fastq
genome
hifi
Drug Resistance Marker Detection
Generate a report summarizing drug resistance markers detected in a given set of variant calls.
annotation
drug-resistance
long-read
variants
DRAGEN - Whole Genome Germline Single Sample Analysis
DRAGEN functional equivalence germline SNP and indel discovery in human whole genome sequencing data.
dragen
DRAGEN - Variant Calling and Filtering
DRAGEN functional equivalence discovery and filtering of SNPs and indels.
dragen
filtering
variants
Sentieon Long Read Germline Whole Genome Sequencing Analysis
Perform alignment and variant calling for SNPs, small indels, and structural variants using Sentieon.
alignment
fastq
long-read
sentieon
variants
wgs
Sentieon Germline Whole Genome Sequencing Analysis
Align reads to the reference genome, call variants, and calculate quality metrics using Sentieon.
alignment
germline
variants
wgs
Sentieon Somatic Variant Calling
Compare tumor/normal samples and call somatic variants using Sentieon.
alignment
normal
tumor
variants
Whole Genome Variant Calling
Call small and structural variants using Oxford Nanopore data.
alignment
long-read
mtDNA
structural variants
variants